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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANXA2 All Species: 27.27
Human Site: S277 Identified Species: 66.67
UniProt: P07355 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07355 NP_001002857.1 339 38604 S277 F A D R L Y D S M K G K G T R
Chimpanzee Pan troglodytes A5A6M2 346 38724 A285 F A E K L H Q A M K G V G T R
Rhesus Macaque Macaca mulatta XP_001094593 485 53578 S423 F A D R L Y D S M K G K G T R
Dog Lupus familis XP_545703 305 35697 M244 A D Q P Y N S M K S K G T H D
Cat Felis silvestris
Mouse Mus musculus P07356 339 38658 S277 F A D R L Y D S M K G K G T R
Rat Rattus norvegicus Q07936 339 38660 S277 F A D R L Y D S M K G K G T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510658 389 44505 S327 F A D R L Y D S M K G K G T R
Chicken Gallus gallus P17785 339 38622 S277 F A D R L Y D S M K G K G T R
Frog Xenopus laevis P27006 340 38527 S278 F A D R L Y E S M K G R G T K
Zebra Danio Brachydanio rerio NP_861426 337 38134 A275 F A S R L Q D A M K S K G A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52 69.9 70.2 N.A. 97.6 96.7 N.A. 82 89.6 80.8 66.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 69 69.9 77.2 N.A. 98.8 99.1 N.A. 85.8 95.8 91.1 80.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 60 100 0 N.A. 100 100 N.A. 100 100 80 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 100 0 N.A. 100 100 N.A. 100 100 100 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 90 0 0 0 0 0 20 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 70 0 0 0 70 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 90 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 80 10 90 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 10 90 10 70 0 0 20 % K
% Leu: 0 0 0 0 90 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 10 90 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 10 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 80 0 0 0 0 0 0 0 10 0 0 70 % R
% Ser: 0 0 10 0 0 0 10 70 0 10 10 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 10 80 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 70 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _